Clare left her home in Northern Ireland when she was 16 years old and come and study in Portsmouth.
The 39-year-old is also the only woman in the UK to have run a three-Michelin-star restaurant.
After working for mentor Gordon Ramsay for more than 13 years, she opened her first restaurant, Core by Clare Smyth, last year.
The Notting Hill restaurant is an informal fine dining experience that focuses on simply celebrating sustainable British produce.
Sector Lead for Catering, Hospitality and Travel & Tourism Robert Strachan said: “Congratulations to Clare for winning this award, we’re very honoured to have been a part of her journey. Highbury College has a fantastic and long-standing reputation in the catering industry. We’re very proud that one of our former students has gone on to achieve so much and that her talents have been recognised accordingly. She’s an inspiration to any one of our aspiring students.”